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-MSH is produced in the pituitary gland and is involved in various physiological processes, including skin tanning, energy homeostasis, and the suppression of inflammation
Avraham Y, Mankuta D, Lipsker L, Vorobiev L, Patael S, Hassid G, et al
In the withdrawal trial, continuing preserved loss far better than switching to placebo, which regained about 14% over a year. The metabolic benefit fades in proportion to the weight regained, so a taper plus protein and resistance training beats a hard stop
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