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Avoid Freezing While heat is an enemy, extreme cold is also dangerous
Unused tirzepatide pens must be refrigerated at 36F to 46F and never frozen
Beyond collagen, GHK-Cus effects on the extracellular matrix extend to elastin (30% increase), decorin (302% increase at 1 nanomolar concentration), glycosaminoglycans, dermatan sulfate, and chondroitin sulfate
However, it is especially remarkable that within the SUMMIT trial, among patients with HFpEF, the dual glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide agonist, tirzepatide, significantly reduces the combined risk of cardiovascular death or the exacerbation of HF
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