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Conversely, the M2 phenotype supports tissue repair and synaptic remodeling following the pro-inflammatory phase through the secretion of anti-inflammatory cytokines [i.e., IL-10 and transforming growth factor-beta (TGF-)]
Metformin promotes focal angiogenesis and neurogenesis in mice following middle cerebral artery occlusion
Given the emerging understanding of the gut-testicular axis and how gut-derived endotoxins may suppress testosterone (Tremellen, 2016), this property is potentially relevant to hormone health
It can support metabolic control
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