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Besides the acute phase gastrointestinal effects which may lead to up to 10% of people discontinuing the drugs, there are other potential GI side effects of obstruction, excessive loss of muscle mass, and potentially association with some eye disease adverse events

If left untreated, severe vitamin B12 deficiency can lead to complications such as megaloblastic anemia, nerve damage, and neurological disorders

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A vial left on a counter for three hours during multi-dose preparation has already lost 2535% of its biological activity