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Biochimie 93 , 13921400 (2011)

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Gram-negative bacteria produce LPS, disrupting the intestinal barrier and causing dysbiosis [94, 95]

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Although these caspases cannot directly cleave the precursors of IL-1/IL-18, they can still trigger pyroptosis by cleaving GSDMD-NT, a process specifically activated by bacterial lipopolysaccharides [67, 68]

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