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2008 Apr;145(4):472-7

Combination Therapy: The Synergistic Approach Progressive clinicians have discovered that combining multiple peptides creates synergistic effects

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Human adult dermal fibroblasts incubated with GHK-Cu at concentrations of 0.01, 1, and 100 nM demonstrated increased production of both elastin and collagen, with all concentrations increasing TIMP1 expression and low concentrations enhancing MMP1 and MMP2 gene expression