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Also, decreased glutathione levels caused motor neuron degeneration in the hSOD1 wt over-expressing mice model (hemizygous mice over-expressing wild-type hSOD1 at moderate levels) (Killoy et al., 2018) and accelerated motor neuron death in SOD1 G93A mice (Pehar et al., 2014)
reported that NAC pretreatment conferred protection against sepsis-induced acute kidney injury by alleviating inflammatory damage and oxidative insult in renal tissues (Fan et al., 2020)
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