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Since April 22, 2025, 503A enforcement discretion ended, and the FDA proposed in April 2026 to exclude semaglutide, tirzepatide, and liraglutide from the 503B Bulks List
Headaches : Dehydration can cause headaches or make existing headaches worse
Despite scarce data on GLP-1 distribution for Ozempic and Wegovy, studies report low patient adherence, as those still using the drugs drop to less than a third (32%) after the first year, then to 15% after year two
Bioelectrical impedance analysis (BIA), though less precise and affected by hydration status, offers a practical alternative for tracking trends
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