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They highlighted the need to consider potential tradeoffs between efficacy and side effects, finding that higher doses can have stronger efficacy but also induce more severe side effects

What does a tirzepatide injection site reaction look like The first thing most people notice is redness

The problem surfaced in clinical trials run in 1992 by Mojsov and David Nathan, a physician and expert in type 2 diabetes at MGH, and those of Holst and Nauck (Molteni, Chen)