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Safety and Monitoring Checklist For either route, track objective data: Fasting glucose and/or A1c IGF-1 labs Blood pressure Fluid retention/edema Joint discomfort or carpal tunnel-like symptoms Sleep quality and recovery markers If stacking GH-axis compounds, increase lab frequency and lower starting doses

Sci Rep 6:33072 Stroes ES, Thompson PD, Corsini A, Vladutiu GD, Raal FJ, Ray KK, Roden M, Stein E, Tokgzolu L, Nordestgaard BG, Bruckert E, de Backer G, Krauss RM, Laufs U, Santos RD, Hegele RA, Hovingh GK, Leiter LA, Mach F, Mrz W, Newman CB, Wiklund O, Jacobson TA, Catapano AL, Chapman MJ, Ginsberg HN, European Atherosclerosis Society Consensus Panel, Stroes E, Thompson PD, Corsini A, Vladutiu GD, Raal FJ, Ray KK, Roden M, Stein E, Tokgzolu L, Nordestgaard BG, Bruckert E, Krauss RM, Laufs U, Santos RD, Mrz W, Newman CB, John Chapman M, Ginsberg HN, John Chapman M, Ginsberg HN, de Backer G, Catapano AL, Hegele RA, Kees Hovingh G, Jacobson TA, Leiter L, Mach F, Wiklund O (2015) Statin-associated muscle symptoms: impact on statin therapyEuropean Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management