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Insurers frequently impose BMI thresholds (typically 30 or higher), require documented diet-and-exercise failures, or demand proof of related conditions like type 2 diabetes or cardiovascular disease
Recent findings from the SUSTAIN-7 study demonstrated semaglutide's superiority over dulaglutide in enhancing glycaemic management and facilitating significant weight reduction, while preserving similar safety profiles (Pratley et al
With this compound, weight losses of up to 22% are generated in obese individuals [42], and several of the phase III SURPASS trials of patients with T2DM have shown reductions of HbA 1c to values at or below 5.7% (a completely normal value) in more than 50% of the patients, accompanied by weight losses in the order of 12% [43]
[6] Still, baseline testing may be important if you have a history of liver disease or are taking other medications metabolized by the liver
