And with weight gain comes the return of insulin resistance. If you discontinue the medication, lifestyle interventions can partially preserve insulin sensitivity improvements after you stop taking the meds, says Silvana Obici, MD, the chief of the division of endocrinology at Stony Brook Medicine and the medical director of the Stony Brook University Hospital Diabetes Center in New York
It could indicate inadequate caloric intake, nutritional deficiencies, dehydration, or rarely, an underlying condition unmasked by the metabolic changes
The GLP-1 Clinical Trial Landscape in 2024 Glucagon-Like Peptide-1 (GLP-1), Semaglutide, and other GLP-1 targeting drugs are involved in many clinical trials as of July 2024
Counter to this attitude was the emergence of the body positivity movement in the 2010s that sought to promote self-acceptance, celebrate body shape diversity, and prioritize metabolic health, challenging the use of BMI or weight as sole indicators of health without considering the broader context (Gailey, 2022
