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Overview of main clinical studies for MASLD/MASH with GLP-1 receptor agonists and dual or triple agonists targeting glucagon/GIP/GLP-1 receptors Liraglutide Liraglutide, a once-daily GLP-1 receptor agonist with authorized indications for type 2 diabetes and obesity, was evaluated in the LEAN trial (NCT01237119), a phase 2 randomized controlled study enrolling 52 adults with biopsy-proven MASH [22]
It is especially useful for people who do fasted cardio, train frequently, or want a simple supplement to pair with their weight management goals
b , Blood glucose profile during ipPTT (pyruvate given at dose of 2g/kg) and ( c ) area under the ipPTT curve
Cooper et al
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