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DNA binding activity resides within the disordered C-terminal region of PDS5B, and testing of a DNA binding mutant provides evidence that this PDS5B attribute underpins protein functions in vitro and in HR and replication fork protection in cells
The CagriSema combination may follow a parallel but distinct regulatory pathway, potentially offering an alternative to monotherapy approaches depending on comparative efficacy and safety data
Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis
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