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Nat Rev Endocrinol 19 , 201216 (2023)
In a clinical trial in 42 individuals with type 2 diabetes, 300 mg of a chlorogenic acid-containing plant extract daily for four weeks significantly reduced fasting plasma glucose, C-reactive protein (CRP), and liver enzymes compared with placebo (Abidov 2006)
Steinherz, PG, Gaynon P, Haimi J, Meyers P, Redner A, Steinherz L, Andreeff M , Hammond D
Many patients benefit from combining metformin with SGLT2 inhibitors or GLP1 receptor agonists for added cardiovascular and renal protection
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