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HFE can also reverse the TMAO-induced decrease of antioxidant capacity by upregulating the expression of antioxidant enzymes including superoxide dismutase 1 (SOD1), SOD2, glutathione peroxidase 3 (GSH-Px3), and catalase (CAT) in the liver
GLP-1 patients were responsible for roughly 695 kilograms lower carbon dioxide emissions annually due to a reduction in their daily calorie consumption, compared to those on placebo, researchers found
At this point, switching to a dual or triple agonist like tirzepatide may provide additional benefit
10.1038/s41467-020-20141-z 66
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