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Originally developed by Eli Lilly and now advanced by Innovent in China, Mazdutide recently showed superiority over semaglutide in both glycemic control and weight loss in a Phase 3 study
Efficacy and safety of semaglutide compared with liraglutide and placebo for weight loss in patients with obesity: a randomised, double-blind, placebo and active controlled, dose-ranging, phase 2 trial. GLP-1 and obesity: International Journal of Molecular Sciences (2019)
Figure 4 and Additional file 1: Table S5 show the overall effects of the three classes of drugs on cardiorenal endpoints by the network meta-analysis using the frequentist approach
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