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It's a naturally occurring copper-binding peptide that directly stimulates collagen I, collagen III, and elastin synthesis the structural proteins that make up the annulus fibrosus
Together, these peptides are referenced in preclinical literature for their relationship to receptor-mediated signaling, feedback mechanisms, and metabolic pathway modulation under controlled experimental conditions
Dietary polyphenols such as piceatannol and astringin could strongly inhibit ferroptosis via preferential transfer of hydrogen atoms at the 4-OH position as conventional antioxidants 154,516
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