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It is advisable for patients to maintain open communication with their healthcare provider throughout the process to discuss any changes or concerns
Regulatory agencies continue to monitor psychiatric signals because mood changes may affect a smaller subset of patients
For individuals without insurance coverage, we offer self-pay options to ensure access to this beneficial treatment
Together these observations are consistent with an important concept: microglia are the earliest responders to a primary multifocal myelin injury in the MS white matter, and importantly, this injury/response seems to precede lymphocytic infiltration, arguing against adaptive immune cells being the primary drivers of white matter injury
