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Retatrutides 48-week data may not represent the compounds maximum potential, while longer Mazdutide studies continue generating data

It is worth emphasizing that the gradual approach used did not reduce weight loss or compromise glycemic efficacy, reinforcing that tolerability, not symptom intensity, should guide dose advancement ( A patient centered approach of starting low and going slow prioritizes safety and adherence, building on the principle of doing no harm

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For patients seeking GLP-1s, this difference can be important, Ramachandran said