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7.5 Safety, sex-specificity, and CNS considerations Neuroendocrine and immunemetabolic peptides raise distinct safety considerations that must be addressed explicitly

Studies have shown that adding n-3 LCPUFA to TB treatment regimens reduced M.tb burden [50], decreased systemic and lung inflammation [51], and enhanced weight in M.tb -infected C3HeB/FeJ mice with a sufficient n-3 LCPUFA status [52]

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There was also the diversity of the co-administered medications (statins or coenzyme Q10)