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Green R et al
intrinsic factor 10 The is absorbed by the IF-cobalamin complex and requires calcium: distal ileum Binds to the cubam receptor in the terminal ileum and is internalized)
When B12 levels are low, the signs can be varied: Anemia: fatigue, weakness, pale skin, and dizziness Fatigue: a deep-seated weariness that doesn't improve with rest Nerve Damage: tingling or numbness in hands and feet, balance problems, and memory loss (seek medical advice promptly) Mood Disturbances: depression, irritability, and personality changes While our bodies can store B12 for years, some groups are more susceptible to deficiency, often because of absorption issues rather than diet
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