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3.4 Physical activity recommendations in patients with obesity on GLP-1RAs Patients receiving GLP-1RAs experience significant weight loss but are also at increased risk of lean body mass and bone density loss

Sources: Ligands for Melanocortin Receptors The Melanocortin Receptor System: A Target for Multiple Degenerative Diseases Novel approaches to the design of bioavailable melanotropins Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study Melanotan II injection resulting in systemic toxicity and rhabdomyolysi The product is intended for scientific research and laboratory analysis

A pivotal 2021 clinical trial of semaglutide showed that participants lost an average of 15% of their body weight over 68 weeks, compared to just 2% in the placebo group

Yes, weight loss shots are safe when administered under medical supervision