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Although an increased risk of pancreatitis is listed in product monographs for GLP-1RAs and caution should be exercised in individuals with a history of pancreatitis, causality has not been established [4, 66]
Semaglutide GLP-1, initially developed for managing type 2 diabetes, has been FDA-approved since June 2021 for chronic weight management in adults with obesity or those who are overweight and have at least one weight-related condition such as hypertension, type 2 diabetes, or hyperlipidemia
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