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it is highly active in embryonic cells and cancer cells but largely silenced in most adult somatic cells Epitalon has been shown in in vitro studies to induce telomerase expression in human fetal somatic cells and to produce measurable telomere elongation over culture periods Whether this translates to significant telomere maintenance in adult tissues in vivo, at the doses used in clinical protocols, remains an open research question The telomerase data for Epitalon are interesting and biologically significant, but it is important to be accurate about what they show