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Significantly, deletion of a single allele encoding Glut1 markedly reduces glucose uptake, leading to BBB disruption, a decline in CBF, and ultimately, neuronal death and loss [27]
Intensive performance protocols are reserved for short-term studies focused on acute performance markers like substrate oxidation or mitochondrial respiration, where higher frequency justifies the added complexity
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doi: 10.1038/s41573-018-0008-x 50 CunhaL
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