Excessive astrocytic GABA causes cortical hypometabolism and impedes functional recovery after subcortical stroke
Hong S-S, Oh KT, Choi H-G, Lim S-J (2019) Liposomal Formulations for Nose-to-Brain Delivery: Recent Advances and Future Perspectives
Additionally, EVs derived from steatotic hepatocytes or lipid-laden muscle cells have been shown to carry specific lipid cargo (e.g., ceramides) and microRNAs that can be delivered to recipient cells, such as vascular smooth muscle cells, promoting their phenotypic switch to a pro-calcific, pro-inflammatory state, thereby accelerating atherosclerotic plaque maturation and instability (101, 102)
Effects of tesamorelin, a growth hormone-releasing factor, in HIV-infected patients with abdominal fat accumulation: A randomized placebo-controlled trial with a safety extension