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It has been confirmed that patients with T2DM have a higher risk of developing NDD, including AD, PD, amyotrophic lateral sclerosis and Huntingtons disease, which in these patients are accompanied by more pronounced motor deficits and faster disease progression

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A retrospective study of 974 otherwise healthy women on spironolactone for acne, age 18-45, found a hyperkalemia rate of 0.72% identical to the 0.76% rate in matched women not on the drug

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