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[25] Cancer [edit] In response to a report of precancerous changes in the pancreases of rats and organ donors treated with the DPP-4 inhibitor sitagliptin, [26] [27] the US FDA and the European Medicines Agency each undertook independent reviews of all clinical and preclinical data related to the possible association of DPP-4 inhibitors with pancreatic cancer

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Pfizers move to acquire Metsera followed recent setbacks in Pfizers in-house drug candidates for obesity

The obesity crisis has become a global health emergency with over a billion people living with obesity in the world, creating global opportunities for weight-loss drugmakers