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When pain limits your options If youre managing a musculoskeletal condition like back pain or arthritis, low-impact options put less stress on joints while still supporting cardiovascular fitness: Swimming or aquatic exercise (the water supports your weight) Cycling, including stationary bikes Yoga or pilates for flexibility and strength Walking at a pace that feels comfortable Your GP or physiotherapist can advise on appropriate activities for your specific situation

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Retatrutide, a triple agonist targeting GIP, GLP-1, and glucagon receptors, achieved 24.2% weight loss in Phase 2 trials

At the concentrations used (typically 2 mg/mL), niacinamide is invisible in solution