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Additionally, two long-chain omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), can be synthesized from ALA, but their synthesis may be insufficient under certain conditions, such as during pregnancy and lactation (87, 88)
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In vivo, apigenin treatment prevented infiltration and degranulation of mast cells, while suppressing IL-31 in the skin [134]
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