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The landmark SURMOUNT-5 trial compared the two drugs directly over 72 weeks: On paper, tirzepatide wins on raw weight loss
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First, because it penetrates only a few millimeters, it avoids harming healthy tissue further away from the tumor
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![GLP-1 Weight-Loss Medication Glucagon-like peptide-1 (GLP-1) receptor agonists (semaglutide [Wegovy, Ozempic, Rybelsus]) and dual incretin agonists (tirzepatide [Zepbound, Mounjaro]) are popular treatments for obesity. The authors discuss the kind of](https://lookaside.fbsbx.com/lookaside/crawler/media/?media_id=1050961973852737)
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