Whilst the market is currently led by Novo Nordisks semaglutide (Ozempic/Wegovy) and Eli Lillys tirzepatide (Mounjaro/Zepbound), stronger competition is expected with new entrants (Boehringer Ingelheim, Amgen, Pfizer, Roche amongst others) offering novel mechanisms (dual agonists, triple agonists and amylins), formulations (oral vs injectable) and dosing regimens (daily vs weekly vs monthly).
Effect of alcohol abuse and glutathione administration on the circulating levels of glutathione and on antipyrine metabolism in patients with alcoholic liver cirrhosis
Medications that may be effective against nausea and diarrhea are antiemetic drugs, although evidence is limited: Benadryl, Bonine, Phenergan, Dramamine, Gravol
Several FDA-approved alternatives exist right now, including new oral GLP-1 options and generic liraglutide