Currently, FDA approval exists only for submental (under-chin) use, so arm treatments are considered off-label
There are a bunch of other inborn errors of metabolism, including short-chain acyl-CoA dehydrogenase deficiency and medium-chain acyl-CoA dehydrogenase deficiency.[ref] Lets look at the inborn errors of metabolism involving carnitine: CPT2 gene: The CPT2 gene encodes the enzyme that moves fatty acids attached to carnitine into the inner membrane of the mitochondria
Braun TP, Orwoll B, Zhu X, Levasseur PR, Szumowski M, Nguyen ML, et al
While generally considered safe, long-term or high-dose DFO administration can still lead to neurotoxicity or organ damage (Zhang et al., 2025), and it requires slow infusion due to the risk of hypotension (Gerhardsson, 2022)