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Taking your dose one day early compresses the dosing interval slightly but does not typically cause harm or require dose adjustment

It's not this huge burst of inflammation that you get from something like exercise where your body is responding to that with an anti inflammatory response

Without in-person medical oversight, dosing errors which have caused hospitalisations can go undetected

Historically, this increased insulin response mediated by GLP-1 and GIP had been attributed to factors termed incretins (derived from incretion, a term used at that time to refer to a secretion that remains inside the body), hence the name incretin effect is still used today to describe the rise in insulin mediated by the action of these hormones