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Faster rates, while sometimes achievable short term, rarely sustain long term and may indicate excessive caloric restriction that will trigger metabolic adaptation

Researchsupported contexts Cystic Fibrosis Chronic otitis media with effusion HIVpositive individuals Idiopathic Pulmonary Fibrosis Chronic rhinitis Chronic smoking* and emphysema* *Both have been linked with lower glutathione levels in the epithelial lining fluid