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Description

Bupropion stimulates pro-opiomelanocortin cells (POMC) to produce an anorexic effect, and when paired with naltrexone HCl, inhibits a negative feedback loop that may reduce efficacy of bupropion

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Afamelanotide (Scenesse) is the FDA-approved pharmaceutical formulation with proven safety and efficacy from Phase 3 clinical trials, delivered as a controlled-release subcutaneous implant

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L-carnitine administration was able to reduce the production of ketone bodies in the hepatocyte under starvation [27]

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