Women with PCOS often have insulin resistance, elevated androgens, and metabolic dysfunction that may affect treatment response
The suggestion that progressive emphysematous destruction is associated with down-regulation of genes involved in or downstream of tissue remodeling and wound repair pathways supports a role for defects in ECM homeostasis and angiogenesis in the emphysematous destruction that occurs with chronic inflammation in COPD
31 Examples include cardiovascular diseases, cancer, neurodegenerative diseases, diabetes, and chronic hepatic diseases
doi:10.1210/clinem/dgad487 Daniel, S., Waggett, S., Lyles, E., Sagut, P., Shamaei Zadeh, P., Marcelletti, A., Stegura, C., & Wine Lee, L