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But because of potential toxic side-effects, direct infusion of immune-stimulatory cytokines have not been used
A diagnosis of GSSD was finally made based on intractable metabolic acidosis, jaundice, hemolytic anemia, hyperbilirubinemia, massive 5-oxoprolinuria, and the presence of compound heterozygous variants in GSS
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However, the chemical composition of GSH does not allow it to be taken orally for central nervous system diseases because little to none crosses the blood-brain barrier
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